منابع مشابه
The Production of Creatinuria in Normal Adults
As a result of numerous investigations made in the thirteen years which have elapsed since the publication of Folin’s method for the determination of creatine and creatinine, it is now a generally accepted fact that creatine does not occur in the urine of normal men living on a creatine-free diet. Until a few years ago it was believed that this statement applied also to normal non-pregnant wome...
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One of the immediate effects of hypophysectomy is a loss of nitrogen (1) and a corresponding loss in weight (2). This change is reflected clinically by the so-called cachexia of Simmonds' disease (3). Nitrogen balance is then re-established at a lower level of body weight with lessened food intake. In the experimental animal, adequate replacement therapy is readily obtained with anterior hypoph...
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Thirty-eight patients who presented with diabetes and a changed state of consciousness satisfied the criteria for lactic acidosis. Sixteen patients were non-ketotic, and 15 of these were receiving phenformin on admission. In all but one of these 15 patients, however, additional renal or cardiovascular abnormalities, or both, could be identified, which supported a multifactorial aetiology for la...
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Probably the most common mechanism by which metformin elevates blood lactate is by inducing catecholamine release in those who regulate or prescribe it. Caution in restricting the use of metformin for the treatment of type 2 diabetes has been rationalized on the basis of J) its chemical identity as a biguanide, 2) its ability to modify hepatic intermediary metabolism, 3) its administration to i...
متن کاملRumen Acidosis in Small Ruminants and Its Therapeutic Management
Forty two small ruminants, 26 (61.90%) sheep and 16 (38.10%) goats were treated for rumen acidosis. 19 (45.24%), 12 (28.57%), 6 (14.29%) and 5 (11.90%) animals had eaten apple, cooked rice (wazwan left over) turnip and chapatti respectively and manifested clinical form of ruminal acidosis with, 2.86%; (n=18) as mild (Rumen fluid pH=6.32 ±0.09316), 38.09%;(n=16)moderate (Rumen fluid pH=5.71 ±0.0...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1919
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)86356-6